Active Recombinant Human XCL1, HIgG1 Fc-tagged, mutant

Cat.No. : XCL1-159H
Product Overview : The extracellular domain of human XCL1 (AAH70309.1) (Val22-Gly114) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : This gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunologicalresponses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokinesubfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specificallychemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome1
Source : CHO cell
Species : Human
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by its ability to chemoattract BaF3 mouse proB cells.
Molecular Mass : 36KDa (monomer)
AA Sequence : Val22-Gly114
Endotoxin : <0.06 eu/μg="" as="" determined="" by="" lal="">
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
References : 1.Expression and function of the C-class chemokine lymphotactin (XCL1) in Wegener"s granulomatosis. 2.Interconversion between two unrelated protein folds in the lymphotactin native state.
Tag : Fc
Protein length : 22-114 a.a.
Gene Name XCL1 chemokine (C motif) ligand 1 [ Homo sapiens ]
Official Symbol XCL1
Synonyms XCL1; chemokine (C motif) ligand 1; LTN, SCYC1, small inducible cytokine subfamily C, member 1 (lymphotactin); lymphotactin; ATAC; LPTN; SCM 1; SCM 1a; SCM-1-alpha; lymphotaxin; cytokine SCM-1; c motif chemokine 1; XC chemokine ligand 1; single cysteine motif 1a; small-inducible cytokine C1; small inducible cytokine subfamily C, member 1 (lymphotactin); LTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a;
Gene ID 6375
mRNA Refseq NM_002995
Protein Refseq NP_002986
MIM 600250
UniProt ID P47992
Chromosome Location 1q24.2
Pathway Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (q) signalling events, organism-specific biosystem;
Function chemokine activity; chemokine receptor binding; chemokine receptor binding; protein homodimerization activity;

Not For Human Consumption!

Inquiry

  • Reviews
  • Q&As

Customer Reviews (0)

Write a review

Q&As (0)

Ask a question

Ask a Question for All XCL1 Products

Required fields are marked with *

My Review for All XCL1 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon