Active Recombinant Human WNT7A Protein

• Cat.No.: WNT7A-121H
• Product Overview: The mature recombinant human Wnt-7a protein containing 318aa (L32-K349) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes.
• Bio-activity: Measured by its ability to inhibit Wnt-3a-induced alkaline phosphatase production by MC3T3-E1 mouse preosteoblast cells. The ED50 for this effect is 1-3 μg/mL in the presence of 5 ng/mL recombinant mouse Wnt-3a.
• Molecular Mass: 35.5 kDa
• Product-Related Proteins: 32-349
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: WNT7A Wnt family member 7A [ Homo sapiens (human) ]
• Official Symbol: WNT7A
• Synonyms: WNT7A; Wnt family member 7A; Wnt-7a; protein Wnt-7a; Names; proto-oncogene Wnt7a protein; wingless-type MMTV integration site family, member 7A
• Gene ID: 7476
• mRNA Refseq: NM_004625
• Protein Refseq: NP_004616
• MIM: 601570
• UniProt ID: O00755