Active Recombinant Human WNT11 Protein

• Cat.No.: WNT11-113H
• Product Overview: The mature recombinant human Wnt-11 protein containing 330aa (I25-K354) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq, Jul 2008]
• Bio-activity: Measured in a cell proliferation/survival assay using IEC-18 rat small intestinal epithelial cells. The ED50 for this effect is 0.6-2.4 μg/mL.
• Molecular Mass: 36.6 kDa
• Product-Related Proteins: 25-354
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: WNT11 Wnt family member 11 [ Homo sapiens (human) ]
• Official Symbol: WNT11
• Synonyms: WNT11; Wnt family member 11; HWNT11; protein Wnt-11; Names; wingless-type MMTV integration site family, member 11
• Gene ID: 7481
• mRNA Refseq: NM_004626
• Protein Refseq: NP_004617
• MIM: 603699
• UniProt ID: O96014