Active Recombinant Human VEGFD Protein

Cat.No. : VEGFD-198V
Product Overview : Recombinant Human VEGFD Protein without tag was expressed in CHO.
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Species : Human
Source : CHO
Description : Vascular Endothelial Growth Factor (VEGF)-D, also known as c-Fos-induced growth factor (FIGF), is a member of the PDGF/VEGF growth factor family. It is expressed highly in lung, heart and small intestine, and at lower levels in skeletal muscle, colon and pancreas. It binds to VEGFR-2 and VEGFR-3 receptors and activates downstream signals. VEGF-D is a growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth. It is involved in many developmental and physiological processes including the formation of venous and lymphatic vascular systems during embryogenesis and the maintenance of differentiated lymphatic endothelium in adults. In tumor pathology, it has been reported to play a role in restructuring of lymphatic channels and regional lymph node metastasis.
Form : Sterile Filtered White lyophilized (freeze-dried) powder.
Bio-activity : ED50 < 1 μg/mL, measured in a cell proliferation assay using HUVEC cells.
Molecular Mass : 18-19 kDa, observed by reducing SDS-PAGE.
AA Sequence : FAATFYDIETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTAPRHPYSIIRR
Endotoxin : < 0.2 EU/μg, determined by LAL method.
Purity : > 95% as analyzed by SDS-PAGE and HPLC.
Storage : Lyophilized recombinant Human VEGF-D remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, Human VEGF-D should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade.
Storage Buffer : Lyophilized after extensive dialysis against PBS.
Reconstitution : Reconstituted in ddH2O or PBS at 100 μg/mL.
Gene Name VEGFD vascular endothelial growth factor D [ Homo sapiens (human) ]
Official Symbol VEGFD
Synonyms VEGFD; vascular endothelial growth factor D; FIGF; VEGF-D; vascular endothelial growth factor D; c-fos induced growth factor (vascular endothelial growth factor D)
Gene ID 2277
mRNA Refseq NM_004469
Protein Refseq NP_004460
MIM 300091
UniProt ID O43915

Not For Human Consumption!

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