Active Recombinant Human UNC5A Protein, Fc Chimera

• Cat.No.: UNC5A-811H
• Product Overview: Recombinant Human UNC5A (Accession # NP_588610), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc
• Predicted N Terminal: No results obtained: Gln26 predicted
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.When Recombinant Human Netrin-1 is immobilized at 2 µg/mL (100 µL/well), the concentration of Recombinant Human UNC5H1 Fc Chimera that produces 50% of the optimal binding response is found to be approximately 0.3-1.5 µg/mL.
• Molecular Mass: Recombinant Human UNC5A, Fc Chimera has a calculated MW of 57.9 kDa (monomer). In SDS-PAGE migrates as 80-90 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: UNC5A unc-5 homolog A (C. elegans) [ Homo sapiens ]
• Official Symbol: UNC5A
• Synonyms: UNC5A; unc-5 homolog A (C. elegans); unc5 (C.elegans homolog) a; netrin receptor UNC5A; KIAA1976; UNC5H1; unc-5 homolog 1; netrin receptor Unc5h1; protein unc-5 homolog 1; protein unc-5 homolog A; FLJ16449
• Gene ID: 90249
• mRNA Refseq: NM_133369
• Protein Refseq: NP_588610
• MIM: 607869
• UniProt ID: Q6ZN44
• Chromosome Location: 5q35.3