Active Recombinant Human TNFRSF21, Fc-tagged, Biotinylated

• Cat.No.: TNFRSF21-599H
• Product Overview: The recombinant human DR6-Fc fusion is expressed as a 536 amino acid protein consisting of Gln42 - His349 region of DR6 (UniProt accession #O75509) and a C-terminal Fc from human IgG1, which exists as a dimer/tetramer under non-reducing conditions.

Specification

• Species: Human
• Source: Human Cells
• Tag: Fc
• Protein Length: 42-349 a.a.
• Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
• Bio-activity: Binds to human APP or APLP2.
• Molecular Mass: Calculated molecular mass (kDa): 59; Estimated by SDS-PAGE under reducing condition (kDa): 75-85
• Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the
• Purity: >95% judged by SDS-PAGE under reducing condition
• Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: TNFRSF21 tumor necrosis factor receptor superfamily, member 21 [ Homo sapiens ]
• Official Symbol: TNFRSF21
• Synonyms: TNFRSF21; tumor necrosis factor receptor superfamily, member 21; tumor necrosis factor receptor superfamily member 21; CD358; death receptor 6; DR6; TNFR-related death receptor 6; BM-018; MGC31965
• Gene ID: 27242
• mRNA Refseq: NM_014452
• Protein Refseq: NP_055267
• MIM: 605732
• UniProt ID: O75509
• Chromosome Location: 6p21.1
• Pathway: Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem
• Function: protein binding; receptor activity