Recombinant Human TNFRSF21 Protein, hIgG-His-tagged

• Cat.No.: TNFRSF21-001H
• Product Overview: Recombinant human TNFRSF21 protein(42-349aa), fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His&Fc
• ProteinLength: 42-349 a.a.
• Description: TNFRSF21, also known as tumor necrosis factor receptor superfamily member 21, is a transmembrane protein in the TNF receptor superfamily. It promotes apoptosis through the activation of NF-kappa-B pathway. Binding of N-terminal APP (N-APP) and TNFRSF21 triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). This protein plays a role in signaling cascades triggered by stimulation of T-cell receptor.
• Form: Liquid
• Molecular Mass: 60.4 kDa
• AASequence: QPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHEVPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNHQQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
• N-terminal Sequence Analysis: Gln 42
• Endotoxin: < 1.0 EU per 1 μg of protein (determined by LAL method)
• Purity: > 85% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/mL (determined by Absorbance at 280nm)
• Storage Buffer: In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol, 0.1mM PMSF.
• Warning: For research use only. This product is not intended or approved for human, diagnostics or veterin

Gene Information

• Gene Name: TNFRSF21 TNF receptor superfamily member 21 [ Homo sapiens (human) ]
• Official Symbol: TNFRSF21
• Synonyms: TNFRSF21; TNF receptor superfamily member 21; DR6; CD358; BM-018
• Gene ID: 27242
• mRNA Refseq: NM_014452
• Protein Refseq: NP_055267
• MIM: 605732
• UniProt ID: O75509