Species : |
Human |
Source : |
HEK293 |
Tag : |
Non |
Protein Length : |
Cys27-Pro220 |
similar : |
TIMP2 |
Alias : |
TIMP2; TIMP metallopeptidase inhibitor 2; tissue inhibitor of metalloproteinase 2; metalloproteinase inhibitor 2; CSC 21K; TIMP-2; tissue inhibitor of metalloproteinases 2; CSC-21K; |
Conjugate : |
N/A |
Form : |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bioactivity : |
Measured by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate MCA-PLGL-DPA-AR-NH2. The IC50 value is < 4 nM. |
MolecularMass : |
The recombinant human TIMP2 consists of 195 amino acids and has a predicted molecular mass of 22 kDa. It migrates as an approximately 20 kDa band in SDS-PAGE under reducing conditions. |
Endotoxin : |
< 1.0 EU per μg of the protein as determined by the LAL method |
Purity : |
> 96 % as determined by SDS-PAGE |
Storage : |
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
GeneName : |
TIMP2 TIMP metallopeptidase inhibitor 2 [ Homo sapiens ] |
GeneNameWeblink : |
7077 |
OfficialSymbol : |
TIMP2 |
OfficialSymbolWeblink : |
7077 |
GeneID : |
7077 |
GeneIDWeblink : |
7077 |
mRNARefseq : |
NM_003255 |
mRNARefseqWeblink : |
NM_003255.4 |
ProteinRefseqWeblink : |
NP_003246.1 |
MIMWeblink : |
188825 |
UniProtID : |
P16035 |
UniProtIDWeblink : |
P16035 |