Active Recombinant Human TGFB3 Protein, Animal Free

• Cat.No.: TGFB3-48H
• Product Overview: Recombinant Human TGFB3 Protein without tag was expressed in Human cells.
  Animal Free and Xeno Free

Specification

• Species: Human
• Source: Human Cells
• Description: Transforming growth factor beta 3(TGF β3) is one of three closely related mammalian members of the large TGF β superfamily, TGF-β1, β2, and β3, signal through the same receptor and elicit similar biological responses. The mammalian TGF-β3 controls a vast array of biological processes including immune regulation, cell proliferation, epithelial-mesenchymal transition, and the bone formation. It is generally recognized to facilitate chondrogenic differentiation of precursor cells. It may also have a dose-dependent inhibitory effect on osteogenesis.
• Bio-activity: The activity was measured by its ability to inhibit the IL-4 induced proliferation in mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).
• Molecular Mass: 25 kDa
• Endotoxin: <0.5 EU/ μg
• Purity: High Purity, >95% by SDS-PAGE
• Stability: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein
• Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: TGFB3 transforming growth factor, beta 3 [ Homo sapiens (human) ]
• Official Symbol: TGFB3
• Synonyms: TGFB3; transforming growth factor, beta 3; transforming growth factor beta-3; TGF-beta-3; ARVD; TGF-beta3; FLJ16571
• Gene ID: 7043
• mRNA Refseq: NM_003239
• Protein Refseq: NP_003230
• MIM: 190230
• UniProt ID: P10600