Active Recombinant Human TGFB2 Protein, Animal Free

• Cat.No.: TGFB2-47H
• Product Overview: Recombinant Human TGFB2 Protein without tag was expressed in Human cells.
  Animal Free and Xeno Free

Specification

• Species: Human
• Source: Human Cells
• Description: Transforming growth factor beta 2 (TGF-β2) is one of three closely related mammalian members of the large TGFβ superfamily, TGF-β1, β2, and β3, signal through the same receptor and elicit similar biological responses. TGF-β2 is expressed in keratinocytes, granulosa cells, astrocytes, osteoblasts, mammary cells, and various cancer cells. TGF-β2 is secreted and complexed with two other proteins, LAP and TGFBP, and requires proteolytic cleavage to be active. Human TGF-β2 is a secreted, homodimer linked by intermolecular disulfide bonds that plays a role in many cellular processes, including embryogenesis and angiostasis. TGF-β2 also plays an extensive role in prenatal development.
• Bio-activity: The activity was measured by its ability to inhibit the IL-4 induced proliferation in mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).
• Molecular Mass: 25 kDa
• Endotoxin: <0.5 EU/ μg
• Purity: High Purity, >95% by SDS-PAGE
• Stability: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein
• Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: TGFB2 transforming growth factor, beta 2 [ Homo sapiens (human) ]
• Official Symbol: TGFB2
• Synonyms: TGFB2; transforming growth factor, beta 2; transforming growth factor beta-2; G-TSF; cetermin; polyergin; BSC-1 cell growth inhibitor; glioblastoma-derived T-cell suppressor factor; TGF-beta2; MGC116892
• Gene ID: 7042
• mRNA Refseq: NM_001135599
• Protein Refseq: NP_001129071
• MIM: 190220
• UniProt ID: P61812