Active Recombinant Human TBK1 Protein

• Cat.No.: TBK1-010H
• Product Overview: Human recombinant full length TBK1 protein without tag was expressed in insect cells (baculovirus).

Specification

• Species: Human
• Source: Insect Cells
• Protein Length: 1-729
• Description: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.
• Bio-activity: ATPase activity confirmed by ADP detection assay.
• Molecular Mass: 84 kDa
• Purity: ≥50% estimated by SDS-PAGE
• Stability: ≥ 1 year
• Storage: Store at -80 centigrade.
• Storage Buffer: 50 mM HEPES, pH 8.0, with 150 mM sodium chloride, and 10% glycerol

Gene Information

• Gene Name: TBK1 TANK binding kinase 1 [ Homo sapiens (human) ]
• Official Symbol: TBK1
• Synonyms: TBK1; TANK binding kinase 1; NAK; T2K; IIAE8; FTDALS4; serine/threonine-protein kinase TBK1; NF-kB-activating kinase; NF-kappa-B-activating kinase; EC 2.7.11.1
• Gene ID: 29110
• mRNA Refseq: NM_013254
• Protein Refseq: NP_037386
• MIM: 604834
• UniProt ID: Q9UHD2