Active Recombinant Human SULT1A3 Protein

• Cat.No.: SULT1A3-89H
• Product Overview: Recombinant human SULT1A3 protein without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 arose from a segmental duplication. This gene is the most centromeric of the four sulfotransferase genes. Read-through transcription exists between this gene and the upstream SLX1A (SLX1 structure-specific endonuclease subunit homolog A) gene that encodes a protein containing GIY-YIG domains.
• Bio-activity: SULT Activity Data(Unless otherwise stated, all assays are carried out at 37 centigrade in 50 mM potassium phosphate buffer (pH 7.4) containing 5 mM magnesium chloride, 10 mM dithiothreitol and 20 μM PAPS)
  Substrate: 1-naphthol
  Linear with time up to: 12 min(Determined at 5 μM substrate, using a protein concentration of 2 μg/ml)
  Linear with protein up to: 10 μg/ml(Determined at 5 μM substrate, using an incubation time of 5 min)
  Vmax: 32 nmol/min/mg protein
  Km: 4.3 µM
• Usage: For laboratory (research) purposes only
• Storage: Store at -80 centigrade. Avoid frequent temperature changes. Thaw on ice.
• Concentration: Protein Concentration: 10 mg/ml
• Storage Buffer: 10 mM sodium phosphate (pH 7.4), 140 mM NaCl

Gene Information

• Gene Name: SULT1A3 sulfotransferase family 1A member 3 [ Homo sapiens (human) ]
• Official Symbol: SULT1A3
• Synonyms: SULT1A3; sulfotransferase family 1A member 3; STM; HAST; HAST3; M-PST; ST1A3; ST1A4; ST1A5; TL-PST; ST1A3/ST1A4; sulfotransferase 1A3; Sulfotransferase 1A4; aryl sulfotransferase 1A3/1A4; catecholamine-sulfating phenol sulfotransferase; dopamine-specific sulfotransferase; monoamine-sulfating phenosulfotransferase; phenol sulfotransferase 1A5; placental estrogen sulfotransferase; sulfokinase; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; thermolabile (monoamine, M form) phenol sulfotransferase
• Gene ID: 6818
• mRNA Refseq: NM_177552
• Protein Refseq: NP_808220
• MIM: 600641
• UniProt ID: Q1ET61