Active Recombinant Human STK38 Protein, GST/His-tagged

• Cat.No.: STK38-29508H
• Product Overview: Human NDR1, full length, amino acids M1-K465 (as in NCBI/Protein entry NP_009202.1), N-terminal GST-HIS6 fusion protein with a 3C cleavage site, expressed in Sf9 insect cells

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST&His
• Protein Length: 1-465
• Description: This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants.
• Bio-activity: Specific kinase activity (Pi transfer): 2.2 pmol/μg × min
  ATP-KM: 4.5 μM
• Molecular Mass: 82.28 kDa
• Storage: At -80 centigrade.
  For complete recovery, mix well and spin before use. Product must not be stored in diluted solutions, aliquots below 10 μL are not advisable. Avoid repeated freeze-thaw cycles.
• Concentration: 0.266 μg/μL (Bradford method using BSA as standard protein)
• Storage Buffer: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20 % glycerol

Gene Information

• Gene Name: STK38 serine/threonine kinase 38 [ Homo sapiens (human) ]
• Official Symbol: STK38
• Synonyms: STK38; serine/threonine kinase 38; NDR; NDR1; serine/threonine-protein kinase 38; NDR1 protein kinase; Ndr Ser/Thr kinase-like protein; nuclear Dbf2-related kinase 1; EC 2.7.11.1
• Gene ID: 11329
• mRNA Refseq: NM_007271
• Protein Refseq: NP_009202
• MIM: 606964
• UniProt ID: Q15208