Active Recombinant Human SPINT2 Protein, Fc-tagged

• Cat.No.: SPINT2-209H
• Product Overview: Recombinant human SPINT2 (NP_066925.1) (Met1-Lys197) was expressed with the Fc region of human IgG1 at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 1-197 a.a.
• Predicted N Terminal: Ala 28
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Bio-activity: Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-Arg-Pro-Lys-Pro-Val-Glu-NVAL-Trp-Arg-Lys(DNP)-NH2. The IC50 value is< 1 nM.
• Molecular Mass: The recombinant human SPINT2 consists 408 amino acids and predicts a molecular mass of 45.9 kDa.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >90 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: SPINT2 serine peptidase inhibitor, Kunitz type, 2 [ Homo sapiens ]
• Official Symbol: SPINT2
• Synonyms: SPINT2; serine peptidase inhibitor, Kunitz type, 2; serine protease inhibitor, Kunitz type, 2; kunitz-type protease inhibitor 2; HAI 2; Kop; placental bikunin; hepatocyte growth factor activator inhibitor type 2; PB; HAI2; DIAR3; HAI-2; FLJ45571
• Gene ID: 10653
• mRNA Refseq: NM_001166103
• Protein Refseq: NP_001159575
• MIM: 605124
• UniProt ID: O43291
• Chromosome Location: 19q13.2