Active Recombinant Human SMYD5, FLAG-tagged

• Cat.No.: SMYD5-75H
• Product Overview: Recombinant Human Smyd5 (accession number NP_006053.2) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 49 kDa.

Specification

• Description: SET and MYND domain-containing protein 5 (Smyd5) is a member of the Smyd family of histone methyltransferases. Smyd5 has been reported to mediate methylation of H4K20 and may methylate non-histone substrates as well.
• Source: Sf9 insect cells
• Species: Human
• Tag: FLAG
• Form: 20 mM Tris-HCl pH 7.4, 150 mM NaCl and 20% glycerol.
• Bio-activity: Specifically mediates the methylation of H4K20 and may methylate non-histone substrates.
• Applications: Enzyme kinetics, inhibitor screening, and selectivity profiling.
• Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
• Concentration: 0.3 mg/ml

Gene Information

• Gene Name: SMYD5 SMYD family member 5 [ Homo sapiens ]
• Official Symbol: SMYD5
• Synonyms: SMYD5; SMYD family member 5; RAI15, retinoic acid induced 15; SET and MYND domain-containing protein 5; NN8 4AG; RRG1; ZMYND23; retinoic acid induced 15; retinoic acid responsive; retinoic acid-induced protein 15; RAI15; NN8-4AG
• Gene ID: 10322
• mRNA Refseq: NM_006062
• Protein Refseq: NP_006053
• UniProt ID: Q6GMV2
• Chromosome Location: 2p12
• Function: metal ion binding; molecular_function