Active Recombinant Human SIRPG Protein, hIgG/His-tagged

• Cat.No.: SIRPG-09H
• Product Overview: Recombinant human SIRPG (29-360aa), fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Description: The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.
• Source: Insect cell
• Species: Human
• Tag: His&Fc
• Form: Liquid
• Bio-activity: Measured by its binding ability in a functional ELISA with Human CD47. The ED50 range ≤ 1 μg/mL.
• Molecular Mass: 64 kDa (574aa)
• Protein length: 29-360aa
• AA Sequence: EEELQMIQPEKLLLVTVGKTATLHCTVTSLLPVGPVLWFRGVGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRISSITPADVGTYYCVKFRKGSPENVEFKSGPGTEMALGAKPSAPVVLGPAARTTPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPTGQSVAYSIRSTARVVLDPWDVRSQVICEVAHVTLQGDPLRGTANLSEAIRVPPTLEVTQQPMRVGNQVNVTCQVRKFYPQSLQLTWSENGNVCQRETASTLTENKDGTYNWTSWFLVNISDQRDDVVLTCQVKHDGQLAVSKRLALEVTVHQKDQSSDATP
• Endotoxin: < 1 EU/μg of protein (determined by LAL method)
• Purity: > 90% by SDS-PAGE
• Applications: SDS-PAGE, Bioactivity
• Storage: Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/mL (determined by absorbance at 280nm)
• Storage Buffer: Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Gene Information

• Gene Name: SIRPG signal regulatory protein gamma [ Homo sapiens (human) ]
• Official Symbol: SIRPG
• Synonyms: SIRPG; signal regulatory protein gamma; CD172g; SIRPB2; SIRP-B2; bA77C3.1; SIRPgamma; signal-regulatory protein gamma; CD172 antigen-like family member B; CD172g antigen; SIRP beta 2; SIRP-gamma; signal-regulatory protein beta-2
• Gene ID: 55423
• mRNA Refseq: NM_018556
• Protein Refseq: NP_061026
• MIM: 605466
• UniProt ID: Q9P1W8