Active Recombinant Human RAB4B, Member RAS Oncogene Family, GST-tagged

• Cat.No.: RAB4B-1114H

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: Rab4B is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. Rab4 is associated with early endosomes and regulates recycling vesicle formation. Together with Rab5 it acts to control influx and efflux out of early endosomes. The GST-Tag facilitates the protein‘s application in typical GST pull-down assays.
• Usage: For in vitro use only.
• Form: Liquid. Supplied in 50 mM Tris-HCl pH 8.0, 100 mM NaCl, 10 mM MgCl2, 10 μM GDP and 2 mM mercaptoethanol.
• Activity: 100 pmol of protein can bind > 80 pmol of GDP.
• Purity: ≥ 90% by SDS-PAGE.
• Storage: Quality guaranteed for 12 months. Store at -80℃. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: RAB4B RAB4B, member RAS oncogene family [ Homo sapiens ]
• Synonyms: RAB4B; RAB4B, member RAS oncogene family; FLJ78649; MGC52123; ras-related GTP-binding protein 4b; small GTP binding protein RAB4B; Ras-related protein Rab-4B
• Gene ID: 53916
• mRNA Refseq: NM_016154
• Protein Refseq: NP_057238
• MIM: 612945
• UniProt ID: P61018
• Chromosome Location: 19q13.2
• Function: GTP binding; GTPase activity; nucleotide binding