Active Recombinant Human PVRIG Protein, Fc-Avi-tagged, Biotinylated

Cat.No. : PVRIG-617HB
Product Overview : Biotinylated Human PVRIG, Fc, Avi tag is expressed from human 293 cells (HEK293). It contains AA Thr 41-Asp 171 (Accession # Q6DKI7-1).
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Species : Human
Source : HEK293
Tag : Avi&Fc
Protein Length : Thr 41-Asp 171
Description : Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Predicted N Terminal : Thr 41
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 41.9 kDa. The protein migrates as 50-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >90% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name PVRIG
Official Symbol PVRIG
Synonyms C7orf15, C7orf15MGC138295, CD112R, MGC104322, MGC138297, MGC2463, P VRIG, CD112 receptor
Gene ID 79037
mRNA Refseq NM_024070.3
Protein Refseq NP_076975.2
MIM 617012
UniProt ID Q6DKI7

Not For Human Consumption!

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