Active Recombinant Human PTK7 Protein, Fc-tagged

• Cat.No.: PTK7-01H
• Product Overview: Recombinant Human PTK7/CCK4 protein (Met1-Thr704) with Human Human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in Human embryonic kidney cell.

Specification

• Description: This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene
• Source: HEK293
• Species: Human
• Tag: Fc
• Form: Disulfide-linked homodimer
• Bio-activity: Measured by its binding ability in a functional ELISA. In a 100 μL reaction mixture containing biotinylated Recombinant Mouse Wnt-3a at 50 ng/mL and Recombinant Human PTK7/CCK4 Chimera dilutions, the concentration of Recombinant Human PTK7/CCK4 Fc Chimera that produces 50% of the maximal binding response is 4-20 μg/mL.
• Molecular Mass: 101 kDa
• N-terminal Sequence Analysis: Ala31
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: > 95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature.
• Protein length: 1-704 a.a.

Gene Information

• Gene Name: PTK7 protein tyrosine kinase 7 (inactive) [ Homo sapiens (human) ]
• Official Symbol: PTK7
• Synonyms: PTK7; protein tyrosine kinase 7 (inactive); CCK4; CCK-4; inactive tyrosine-protein kinase 7; PTK7 protein tyrosine kinase 7; colon carcinoma kinase 4; pseudo tyrosine kinase receptor 7; tyrosine-protein kinase-like 7; EC 2.7.10.1
• Gene ID: 5754
• mRNA Refseq: NM_002821
• Protein Refseq: NP_002812
• MIM: 601890
• UniProt ID: Q13308