Active Recombinant Human PIP4K2C, GST-tagged

• Cat.No.: PIP4K2C-1459H
• Product Overview: Recombinant full-length human PIP4K2C was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: PIP4K2C (also known as phosphatidylinositol-5-phosphate 4-kinase, type II, gamma) is a member of the PIP kinase family that plays an important role in a wide variety of cell functions. PIP4K2C is found in the cytosol and surrounding plasma membrane and its presence in the endoplasmic reticulum seems to be a prerequisite for PIP2 synthesis. PIP4K2C play an important role in the production of phosphatidylinositol bisphosphate (PIP2) in the endoplasmic reticulum.
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: 5 nmol/min/mg
• Molecular Mass: ~75 kDa
• Purity: >90% by densitometry
• Applications: Kinase Assay; Western Blot
• Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1μg/μl

Gene Information

• Gene Name: PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma [ Homo sapiens ]
• Official Symbol: PIP4K2C
• Synonyms: PIP4K2C; phosphatidylinositol-5-phosphate 4-kinase, type II, gamma; phosphatidylinositol 4 phosphate 5 kinase, type II, gamma , PIP5K2C; phosphatidylinositol-5-phosphate 4-kinase type-2 gamma; FLJ22055; PIP4KII-gamma; PI(5)P 4-kinase type II gamma; phosphatidylinositol 4-phosphate 5-kinase; phosphatidylinositol-4-phosphate 5-kinase, type II, gamma; PIP5K2C
• Gene ID: 79837
• mRNA Refseq: NM_001146258
• Protein Refseq: NP_001139730
• MIM: 600487
• UniProt ID: Q8TBX8
• Chromosome Location: 12q13.2
• Pathway: B Cell Receptor Signaling Pathway; -myo-inositol (1,4,5)-trisphosphate biosynthesis; Phosphatidylinositol signaling system
• Function: 1-phosphatidylinositol-5-phosphate 4-kinase activity; ATP binding; identical protein binding; nucleotide binding; transferase activity