Active Recombinant Human PEAK1, GST-tagged

• Cat.No.: PEAK1-1447H
• Product Overview: Recombinant human PEAK1 (1127-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 1127 aa-end
• Description: PEAK1 or Pseudopodium-enriched atypical kinase 1 is a protein tyrosine kinase which belongs to NKF3 kinase family and regulates the cytoskeleton and has been shown to be involved in cancer progression. PEAK1 promotes anchorage-independent growth in the MDA-MB-435 human cancer cell line and promotes tumor progression of XPA-1 human pancreatic cancer cells when transplanted into the pancreas of nude mice. PEAK1 is highly expressed in spleen, followed by heart, ovary, brain, lung, kidney, and fetal brain.
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: 6 nmol/min/mg
• Molecular Mass: ~100 kDa
• Purity: >95%
• Applications: Kinase Assay, Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.1μg/μl

Gene Information

• Gene Name: PEAK1 NKF3 kinase family member [ Homo sapiens ]
• Official Symbol: PEAK1
• Synonyms: PEAK1; NKF3 kinase family member; pseudopodium-enriched atypical kinase 1; sugen kinase 269; tyrosine-protein kinase SgK269; pseudopodium enriched atypical kinase; SGK269; FLJ21140; FLJ34483; KIAA2002
• Gene ID: 79834
• mRNA Refseq: NM_024776
• Protein Refseq: NP_079052
• Function: ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding