Active Recombinant Human PDCD1LG2, HIgG1 Fc-tagged, mutant

• Cat.No.: PDCD1LG2-586H
• Product Overview: The extracellular domain of human CD273 [PD-L2] (NP_079515.2) (Leu20-Pro219) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.

Specification

• Species: Human
• Source: CHO
• Tag: Fc
• Protein Length: 20-219 a.a.
• Description: PDCD1LG2 (programmed cell death 1 ligand 2) is a protein-coding gene. Diseases associated with PDCD1LG2 include angioimmunoblastic t-cell lymphoma, and oral lichen planus, and among its related super-pathways are Immune System and Phosphorylation of CD3 and TCR zeta chains. GO annotations related to this gene include molecular_function.
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.
• Molecular Mass: 48.6KDa (monomer)
• AA Sequence: Leu20-Pro219
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: PDCD1LG2 programmed cell death 1 ligand 2 [ Homo sapiens ]
• Official Symbol: PDCD1LG2
• Synonyms: PDCD1LG2; programmed cell death 1 ligand 2; B7 dendritic cell molecule; B7 DC; bA574F11.2; Btdc; CD273; PD L2; PDL2; B7-DC; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2; B7DC; PD-L2; PDCD1L2; MGC142238; MGC142240
• Gene ID: 80380
• mRNA Refseq: NM_025239
• Protein Refseq: NP_079515
• MIM: 605723
• UniProt ID: Q9BQ51
• Chromosome Location: 9p24.2
• Pathway: Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem
• Function: molecular_function; protein tyrosine phosphatase activity; receptor activity