Active Recombinant Human PDCD1LG2, HIgG1 Fc-tagged, mutant
| Cat.No. : | PDCD1LG2-586H |
| Product Overview : | The extracellular domain of human CD273 [PD-L2] (NP_079515.2) (Leu20-Pro219) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell. |
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| Description : | PDCD1LG2 (programmed cell death 1 ligand 2) is a protein-coding gene. Diseases associated with PDCD1LG2 include angioimmunoblastic t-cell lymphoma, and oral lichen planus, and among its related super-pathways are Immune System and Phosphorylation of CD3 and TCR zeta chains. GO annotations related to this gene include molecular_function. |
| Source : | CHO cells |
| Species : | Human |
| Tag : | HIgG1 Fc-tagged, mutant |
| Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
| Bio-activity : | Measured by its binding ability in a functional ELISA. |
| Molecular Mass : | 48.6KDa (monomer) |
| AA Sequence : | Leu20-Pro219 |
| Endotoxin : | <0.06 eu/μg="" as="" determined="" by="" lal="" test.=""> |
| Purity : | >98%, by SDS-PAGE under reducing conditions. |
| Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
| Warning : | Avoid freeze/thaw cycles. |
| Protein length : | 20-219 a.a. |
| Gene Name | PDCD1LG2 programmed cell death 1 ligand 2 [ Homo sapiens ] |
| Official Symbol | PDCD1LG2 |
| Synonyms | PDCD1LG2; programmed cell death 1 ligand 2; B7 dendritic cell molecule; B7 DC; bA574F11.2; Btdc; CD273; PD L2; PDL2; B7-DC; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2; B7DC; PD-L2; PDCD1L2; MGC142238; MGC142240; |
| Gene ID | 80380 |
| mRNA Refseq | NM_025239 |
| Protein Refseq | NP_079515 |
| MIM | 605723 |
| UniProt ID | Q9BQ51 |
| Chromosome Location | 9p24.2 |
| Pathway | Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem; |
| Function | molecular_function; protein tyrosine phosphatase activity; receptor activity; |
Not For Human Consumption!
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