Active Recombinant Human NGF Protein

• Cat.No.: NGF-091H
• Product Overview: The mature recombinant human β-NGF protein consists of 120 amino acids without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
• Bio-activity: Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.2-2 ng/mL.
• Molecular Mass: 13.5 kDa
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: NGF nerve growth factor [ Homo sapiens (human) ]
• Official Symbol: NGF
• Synonyms: NGF; nerve growth factor; NGFB; HSAN5; Beta-NGF; beta-nerve growth factor; Names; nerve growth factor (beta polypeptide); nerve growth factor, beta subunit; pro-nerve growth factor long
• Gene ID: 4803
• mRNA Refseq: NM_002506
• Protein Refseq: NP_002497
• MIM: 162030
• UniProt ID: P01138