Active Recombinant Human Neurexophilin 1, His-tagged

• Cat.No.: NXPH1-056H
• Product Overview: Recombinant Human NXPH1protein was expressed in Murine myeloma cell line with a C-terminal 6-His tag.Ala22-Gly271.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: His
• Protein Length: 22-271 a.a.
• Description: NXPH1 is one of atleast four vertebrate neuropeptidelike secreted glycoproteins in theneurexophilin family. The 271 amino acid (aa) NXPH1 sequence contains a 21 aasignal peptide, an 86 aa propeptide that is cleaved at a basic motif, and a164 aa mature protein that contains three potential N-glycosylation sites inthe N-terminal portion and six conserved cysteines in the C-terminal portion.Mature human NXPH1 shares 99% aa identity with mouse, rat, equine, bovine andcanine NXPH1.
• Form: Lyophilized from a0.2 μm filtered solution in PBS.
• N-terminalSequence: Ala22
• Molecular Weight: 29.4 kDa
• Activity: Measuredin a competitive binding assay. When rrNXPH1α is immobilized at 1 μg/mL (100 μL/well), rhNXPH1 inhibits 50% binding of biotinylated rrNXPH1 (250 ng/mL) at the concentration range of 1-3 μg/mL.
• Endotoxin Level: <1.0 EUper 1 μg of the protein by the LAL method.
• SDS-PAGE: 40-60kDa, reducing conditions
• Purity: >90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
• Reconstitution: Reconstituteat 100 μg/mL in sterile PBS
• Storage: Use a manualdefrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt,-20 to -70°C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to -70°C under sterile conditions after reconstitution.

Gene Information

• Gene Name: NXPH1 neurexophilin 1 [ Homosapiens ]
• Official Symbol: NXPH1
• Synonyms: NXPH1; neurexophilin1; NPH1; Nbla00697; neurexophilin-1; OTTHUMP00000200862
• Gene ID: 30010
• mRNA Refseq: NM_152745
• Protein Refseq: NP_689958
• MIM: 604639
• UniProt ID: P58417
• Chromosome Location: 7p22
• Function: receptor binding