Active Recombinant Human NCR1, Fc Chimera

• Cat.No.: NCR1-342H
• Product Overview: Recombinant Human NCR1 (Accession # AAH64806) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Fc
• Predicted N Terminal: No results obtained: Gln22 predicted
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to bind Recombinant Human Vimentin in a functional ELISA with an estimated KD < 2 nM. Garg, A. et al. (2006) J. Immunol. 177:6192.
• Molecular Mass: Recombinant Human NCR1, Fc Chimera has a calculated MW of 53 kDa (monomer). In SDS-PAGE migrates as 60-80 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: NCR1 natural cytotoxicity triggering receptor 1 [ Homo sapiens ]
• Official Symbol: NCR1
• Synonyms: NCR1; natural cytotoxicity triggering receptor 1; LY94, lymphocyte antigen 94 (mouse) homolog (activating NK receptor; NK p46); CD335; NK p46; NKP46; NK cell-activating receptor; natural killer cell p46-related protein; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); LY94; NK-p46; FLJ99094
• Gene ID: 9437
• mRNA Refseq: NM_001145457
• Protein Refseq: NP_001138929
• MIM: 604530
• UniProt ID: O76036
• Chromosome Location: 19