Active Recombinant Human/Mouse TGFB3 Protein

• Cat.No.: TGFB3-245H
• Product Overview: Recombinant Human/Mouse TGFB3 Protein without tag was expressed in E. coli.

Specification

• Species: Human/Mouse
• Source: E.coli
• Description: Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-β3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.
• Bio-activity: Inhibition of IL-4-induced HT-2 cell proliferation, ≤1 ng/mL
• Molecular Mass: Dimer, 12.9/25.7 kDa (113/226 aa)
• AA Sequence: MALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
• Endotoxin: ≤1 EUs/μg, Kinetic LAL
• Purity: ≥95%, Reducing and Non-Reducing SDS PAGE
• Stability: 12 months from date of receipt when stored at 4 centigrade as supplied.
• Storage: Storage: Centrifuge vial before opening. DO NOT VORTEX. Store at 4 centigrade.
• Concentration: 0.25 mg/mL
• Storage Buffer: In solution: 10 mM acetic acid and 20% Ethanol
• Shipping: Ice pack

Gene Information

• Gene Name: TGFB3 transforming growth factor, beta 3 [ Homo sapiens (human) ]
• Official Symbol: TGFB3
• Synonyms: TGFB3; transforming growth factor, beta 3; transforming growth factor beta-3; TGF-beta-3; ARVD; TGF-beta3; FLJ16571
• Gene ID: 7043
• mRNA Refseq: NM_003239
• Protein Refseq: NP_003230
• MIM: 190230
• UniProt ID: P10600