Active Recombinant Human LYN Protein, GST-tagged

• Cat.No.: LYN-252H
• Product Overview: Recombinant human LYN isoform a (NP_002341.1) (Met 1-Pro 512) was fused with the GST tag at the N-terminus.

Specification

• Source: Baculovirus-Insect Cells
• Species: Human
• Tag: GST
• Predicted N Terminal: Met
• Form: Supplied as sterile 50mM Tris, 100mM NaCl, pH 8.0, 0.5mM Reduced Glutathione, 10% gly, 0.5mM PMSF.
• Bio-activity: The specific activity was determined to be 30 nmol/min/mg using Poly(Glu,Tyr) 4:1 as substrate.
• Molecular Mass: The recombinant human LYN/GST chimera consists of 736 amino acids and predicts a molecular mass of 84.8 kDa. It migrates as an approximately 75 kDa band in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >94 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Protein length: 1-512 a.a.

Gene Information

• Gene Name: LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog [ Homo sapiens ]
• Official Symbol: LYN
• Synonyms: LYN; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; tyrosine-protein kinase Lyn; JTK8; lck/Yes-related novel protein tyrosine kinase; p53Lyn; p56Lyn; FLJ26625
• Gene ID: 4067
• mRNA Refseq: NM_001111097
• Protein Refseq: NP_001104567
• MIM: 165120
• UniProt ID: P07948
• Chromosome Location: 8q13
• Pathway: Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem