Active Recombinant Human LTK Protein, GST-tagged

• Cat.No.: LTK-4586H
• Product Overview: Human LTK (NP_002335.2, 498 a.a. - 796 a.a.) partial recombinant protein with GST tag expressed in baculovirus infected Sf21 cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Protein Length: 498-796 a.a.
• Description: The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
• Form: Liquid
• Bio-activity: The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000.
  Substrate: Srctide.
  ATP: 100 μM.
• Molecular Mass: 60 kDa
• Purity: 87 % by SDS-PAGE/CBB staining
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)

Gene Information

• Gene Name: LTK leukocyte receptor tyrosine kinase [ Homo sapiens ]
• Official Symbol: LTK
• Synonyms: LTK; leukocyte receptor tyrosine kinase; leukocyte tyrosine kinase; leukocyte tyrosine kinase receptor; TYK1; protein tyrosine kinase 1
• Gene ID: 4058
• mRNA Refseq: NM_001135685
• Protein Refseq: NP_001129157
• MIM: 151520
• UniProt ID: P29376