Active Recombinant Human LGALS9, His-tagged

• Cat.No.: LGALS9-7105H
• Product Overview: Recombinant Galectin-9 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-148aa
• Description: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl.
• Bio-activity: The ED50 for this effect is is 1.25 - 5 ug/ml. Measured by its ability to agglutinate human red blood cells.
• Molecular Mass: 18.5kDa (168aa), confirmed by MALDI-TOF.
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MAFSGSQAPY LSPAVPFSGT IQGGLQDGLQ ITVNGTVLSS SGTRFAVNFQ TGFSGNDIAF HFNPRFEDGG YVVCNTRQNG SWGPEERKTH MPFQKGMPFD LCFLVQSSDF KVMVNGILFV QYFHRVPFHR VDTISVNGSV QLSYISFQ
• Purity: > 90% by SDS - PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: LGALS9 lectin, galactoside-binding, soluble, 9 [ Homo sapiens ]
• Official Symbol: LGALS9
• Synonyms: LGALS9; lectin, galactoside-binding, soluble, 9; HUAT; LGALS9A; MGC117375; MGC125973; MGC125974; galectin-9; gal-9; ecalectin; galectin 9; tumor antigen HOM-HD-21; urate transporter/channel protein
• Gene ID: 3965
• mRNA Refseq: NM_009587
• Protein Refseq: NP_033665
• MIM: 601879
• UniProt ID: O00182
• Chromosome Location: 17q11.2
• Function: carbohydrate binding; galactose binding; signal transducer activity