Active Recombinant Human KYNU Protein, His-tagged

• Cat.No.: KYNU-253H
• Product Overview: The recombinant human KYNU consists of 475 amino acids and predicts a molecular mass of 53.7 kDa. The apparent molecular mass of rhKYNU is approximately 47 kDa in SDS-PAGE under reducing conditions.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Predicted N Terminal: Met
• Form: Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0, 25% gly, 5%~8% trehalose and mannitol.
• Bio-activity: Measured by its ability to oxidize 3-hydroxykynurenine. The specific activity is >200 pmoles/min/μg.
• Molecular Mass: The recombinant human KYNU consists of 475 amino acids and predicts a molecular mass of 53.7 kDa. The apparent molecular mass of rhKYNU is approximately 47 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >92 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: KYNU kynureninase [ Homo sapiens ]
• Official Symbol: KYNU
• Synonyms: KYNU; kynureninase; kynureninase (L kynurenine hydrolase); L kynurenine hydrolase; kynureninase (L-kynurenine hydrolase)
• Gene ID: 8942
• mRNA Refseq: NM_001032998
• Protein Refseq: NP_001028170
• MIM: 605197
• UniProt ID: Q16719
• Chromosome Location: 2q22.2
• Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; NAD biosynthesis II (from tryptophan), organism-specific biosystem; Selenium Pathway, organism-specific biosystem; Tryptophan catabolism, organism-specific biosystem; Tryptophan metabolism, organism-specific biosystem