Active Recombinant Human INSR Protein, GST-tagged

• Cat.No.: INSR-5093H
• Product Overview: Human INSR (NM_000208, 989 a.a. - 1382 a.a.) partial recombinant protein with GST tag expressed in Sf9 cells.

Specification

• Description: After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
• Source: Insect cell
• Species: Human
• Tag: GST
• Form: Liquid
• Bio-activity: 533 pmol/μg x min
• Molecular Mass: 70.392 kDa
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Concentration: 0.189 μg/μL
• Storage Buffer: In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
• Protein length: 989-1382 a.a.

Gene Information

• Gene Name: INSR insulin receptor [ Homo sapiens ]
• Official Symbol: INSR
• Synonyms: INSR; insulin receptor; CD220; IR; HHF5
• Gene ID: 3643
• mRNA Refseq: NM_000208
• Protein Refseq: NP_000199
• MIM: 147670
• UniProt ID: P06213