Active Recombinant Human IL33 Protein

• Cat.No.: IL33-066H
• Product Overview: Recombinant Human IL-33 protein containing 159 amino acid residues (Ser112-Thr270) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Protein Length: 112-270 a.a.
• Description: The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene.
• Bio-activity: Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 for this effect is 0.06-0.24 ng/mL.
• Molecular Mass: 17.9 kDa
• Product-Related Proteins: 112-270
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: IL33 interleukin 33 [ Homo sapiens (human) ]
• Official Symbol: IL33
• Synonyms: IL33; interleukin 33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; interleukin-33; Names; DVS27-related protein; interleukin-1 family member 11; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules
• Gene ID: 90865
• mRNA Refseq: NM_033439
• Protein Refseq: NP_254274
• MIM: 608678
• UniProt ID: O95760