Active Recombinant Human IL29, HIgG1 Fc-tagged
| Cat.No. : | IL29-003H |
| Product Overview : | The extracellular domain of human IL-29 (AAI17483.1)(Gly20-Thr200) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell. |
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| Description : | This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). |
| Source : | CHO cell |
| Species : | Human |
| Tag : | HIgG1 Fc-tagged |
| Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
| Bio-activity : | Measured in an anti-viral assay. |
| Molecular Mass : | 46KDa (monomer) |
| AA Sequence : | Gly20-Thr200 |
| Endotoxin : | <0.06 eu/μg="" as="" determined="" by="" lal="" test.=""> |
| Purity : | >98%, by SDS-PAGE under reducing conditions. |
| Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
| Warning : | Avoid freeze/thaw cycles. |
| Protein length : | 20-200 a.a. |
| Gene Name | IL29 interleukin 29 (interferon, lambda 1) [ Homo sapiens ] |
| Official Symbol | IL29 |
| Synonyms | IL29; interleukin 29 (interferon, lambda 1); interleukin 29; interleukin-29; IFNL1; IL 29; IFN-lambda-1; cytokine Zcyto21; interferon lambda-1; interferon-lambda-1; interferon, lambda 1; IL-29; |
| Gene ID | 282618 |
| mRNA Refseq | NM_172140 |
| Protein Refseq | NP_742152 |
| MIM | 607403 |
| UniProt ID | Q8IU54 |
| Chromosome Location | 19q13.13 |
| Pathway | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
| Function | cytokine activity; interleukin-28 receptor binding; receptor binding; |
Not For Human Consumption!
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