Active Recombinant Human IL1R1 Protein (19-328aa), C-His-tagged
Cat.No. : | IL1R1-02H |
Product Overview : | Recombinant human IL1RL1 (19-328aa), fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
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Description : | The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. |
Source : | Baculovirus |
Species : | Human |
Tag : | His |
Form : | Liquid |
Bio-activity : | Measured by its ability to inhibit proliferation using D10.G4.1 mouse helper T cells. The ED50 range ≤10 ng/mL with Human IL-33. |
Molecular Mass : | 36 kDa (318aa) |
Protein length : | 19-328 |
AA Sequence : | KFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFASGQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLMYSTVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQEEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRLSRKNPIDHHS |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 95% by SDS-PAGE |
Applications : | SDS-PAGE, Bioactivity |
Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/mL (determined by absorbance at 280nm) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name | IL1RL1 interleukin 1 receptor like 1 [ Homo sapiens (human) ] |
Official Symbol | IL1RL1 |
Synonyms | IL1RL1; interleukin 1 receptor like 1; T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R; interleukin-1 receptor-like 1; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; interleukin 1 receptor-related protein; EC 3.2.2.6 |
Gene ID | 9173 |
mRNA Refseq | NM_016232 |
Protein Refseq | NP_057316 |
MIM | 601203 |
UniProt ID | Q01638 |
Not For Human Consumption!
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