Active Recombinant Human IL18 (Tyr37-Asp193)

• Cat.No.: IL18-330H
• Product Overview: Active Recombinant Human IL18 (Tyr37-Asp193) was expressed in CHO.

Specification

• Species: Human
• Source: CHO
• Tag: Non
• Protein Length: Tyr37-Asp193
• Form: Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH 7.4.
• Bio-activity: Measured by its ability to induce IFN-gamma secretion by KG‑1 human acute myelogenous leukemia cells. The specific activity of recombinant human IL-18 is > 5.0 x 10^4 IU/mg.
• Molecular Mass: 18.2 kDa
• Endotoxin: ≤ 10 EU/mg by the LAL method.
• Purity: ≥ 95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining.
• Storage: 36 months at -20°C to -80°C in lyophilized state
  7-10 days at 2°C to 8°C under sterile conditions after reconstitution
  6 months at -20°C to -80°C under sterile conditions after reconstitution.
• Reconstitution: It is recommended to redissolve in sterile deionized water.

Gene Information

• Gene Name: IL18 interleukin 18 (interferon-gamma-inducing factor) [ Homo sapiens ]
• Official Symbol: IL18
• Synonyms: IL18; interleukin 18 (interferon-gamma-inducing factor); interleukin-18; IGIF; IL 1g; IL 18; IL1F4; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; IL-18; IL-1g; MGC12320
• Gene ID: 3606
• mRNA Refseq: NM_001243211
• Protein Refseq: NP_001230140
• MIM: 600953
• UniProt ID: Q14116

Q&As

What are the difference between IL18-01HG, IL18-153HG and IL18-500H. (sequence, biological activity, QC, or what do you propose to buy)

IL18-01HG: Sequence: a.a.37-193 Endotoxin: <20 EU/mg Bio-activity: >5.0 x 10^4 IU/mg QC: Activity test, SDS-PAGE, LAL, SEC-HPLC IL18-153HG: Protein length: Tyr37-Asp193 AA Sequence: YFGKLESKLS VIRNLNDQVL FIDQGNRPLF EDMTDSDCRD NAPRTIFIISMYKDSQPRGM AVTISVKCEK ISTLSCENKI ISFKEMNPPD NIKDTKSDIIFFQRSVPGHD NKMQFESSSY EGYFLACEKE RDLFKLILKK EDELGDRSIMFTVQNEDVD Bio-activity: 1.0*10^6IU Measured by its ability to induce IFN-gamma secretion by KG‐1 human acute myelogenous leukemia cells in the presence of TNF-alpha. QC: Activity test, SDS-PAGE, LAL IL18-500H Recombinant Human IL18 will be custom produced upon order. All the sequence, purity, activity, and QC procedures will be optional and decided by our customer.