Active Recombinant Human IL17D protein

• Cat.No.: IL17D-128H
• Product Overview: Recombinant Human IL17D was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Interleukin 17D is a disulfide-linked homodimer belonging to the IL-17 family of proinflammatory cytokines. Members belonging to this family share conserved features of cysteine-knot structures but differ in their N-terminal regions. The T-helper cell produced IL17 family is inducible by IL15 and IL23, and IL17D induces expression of endothelial IL6, IL8, and GM-CSF, and inhibits hemopoiesis of myeloid progenitor cells.
• Form: Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA (with BSA as a carrier protein)
• Bio-activity: The ED50 is 7.5-37.5 ng/mL as determined by its binding ability in a functional ELISA (at a concentration of 1 μg/mL).
• Molecular Mass: 20.5 kDa
• Endotoxin: <1.0 EU/μg of recombinant protein as determined by the LAL method.
• Purity: >95%
• Applications: Cell Assay
• Storage: The lyophilized protein is stable for at least one year from date of receipt at -70 centigrade. Upon reconstitution, this cytokine can be stored in working aliquots at 2 centigrade - 8 centigrade for one month, or at -20 centigrade for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
• Reconstitution: Reconstitute in sterile 4mM HCl at 100μg/mL (containing at least 0.1% human or bovine serum albumin)

Gene Information

• Gene Name: IL17D interleukin 17D [ Homo sapiens ]
• Official Symbol: IL17D
• Synonyms: IL17D; interleukin 17D; interleukin-17D; FLJ30846; IL 17D; IL 22; IL 27; IL27; interleukin 27; interleukin-27; IL-22; IL-27; IL-17D
• Gene ID: 53342
• mRNA Refseq: NM_138284
• Protein Refseq: NP_612141
• MIM: 607587
• UniProt ID: Q8TAD2
• Chromosome Location: 13q11
• Function: cytokine activity