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Description :	Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the type II class of interferons. IFNγ signaling in antigen-presenting cells, and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response. IFNγ is critical for innate and adaptive immunity against viral, protozoal, bacterial infections. IFNγ is secreted by Th1, cytotoxic T cells, NKT cells and NK cells. IFNγ is particularly suitable for human CIK activation along with IL-2.
Source :	Human cells
Species :	Human
Bio-activity :	IFNγ stimulates STAT1 phosphorylation in human lung microvascular endothelial cells. HLMVECs were serum starved in EBM-2 medium containing 2% FBS for overnight then treated with La IFNγ for 5 minutes at the indicated concentrations ranging from 0.5 to 500 ng/mL. Phosphorylated STAT1 (Tyr701) was detected by phosphor STAT1 antibody by Western Blot.
Molecular Mass :	21-25 kDa
Endotoxin :	<0.5 EU/ μg
Purity :	High Purity, >95% by SDS-PAGE
Stability :	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.
Storage Buffer :	Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein
Reconstitution :	Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Gene Name	IFNG interferon gamma [ Homo sapiens (human) ]
Official Symbol	IFNG
Synonyms	IFNG; interferon gamma; IFG; IFI; IMD69; interferon gamma; IFN-gamma; immune interferon
Gene ID	3458
mRNA Refseq	NM_000619
Protein Refseq	NP_000610
MIM	147570
UniProt ID	P01579