Active Recombinant Human IFNAR2 protein, Fc-tagged

• Cat.No.: IFNAR2-214H
• Product Overview: Recombinant Human IFNAR2 protein(Ile 27 - Lys 243), fused with Fc tag, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 27-243 a.a.
• Form: Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.
• Bio-activity: Loaded Human IFN-alpha 1, His Tag on HIS1K Biosensor, can bind Human IFNAR2, Fc Tag with an affinity constant of 19.5 nM as determined in BLI assay (ForteBio Octet Red96e).
• Molecular Mass: This protein carries a human IgG1 Fc tag at the C-terminus.The protein has a calculated MW of 51.4 kDa. The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Proteinlength: Ile27-Lys243
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at:
  -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: IFNAR2 interferon (alpha, beta and omega) receptor 2 [ Homo sapiens ]
• Official Symbol: IFNAR2
• Synonyms: IFNAR2; interferon (alpha, beta and omega) receptor 2; IFNABR; interferon alpha/beta receptor 2; IFN-R-2; IFN-alpha binding protein; IFN-alpha/beta receptor 2; type I interferon receptor 2; interferon alpha binding protein; human interferon alpha/beta receptor; interferon-alpha/beta receptor beta chain; IFN-R; IFNARB; IFN-alpha-REC
• Gene ID: 3455
• mRNA Refseq: NM_000874
• Protein Refseq: NP_000865
• MIM: 602376
• UniProt ID: P48551