Active Recombinant Human HSPD1 protein, His-tagged

• Cat.No.: HSPD1-1555H
• Product Overview: Recombinant full length Human HSPD1, 573 amino acids was expressed in E. coli.

Specification

• Description: This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 20 mM Tris-HCl, pH 7.5, 50 mM KCl, 1 mM DTT, 5 mM MgCl2.
• Bio-activity: The protein has ATPase activity at the time of manufacture of 3.6 μM phosphate liberated/hr/μg protein in a 200 μl reaction at 37 centigrade (pH7.5) in the presence of 20 μl of 1 mM ATP using a Malachite Green assay.
• Molecular Mass: 60 kDa
• Storage: Stable for 2 years at -70 centigrade from date of shipment. Please aliquot to avoid repeated freezing and thawing.
• Full Length: Full L.
• Protein length: 1-573 a.a.

Gene Information

• Gene Name: HSPD1 heat shock 60kDa protein 1 (chaperonin) [ Homo sapiens ]
• Official Symbol: HSPD1
• Synonyms: HSPD1; heat shock 60kDa protein 1 (chaperonin); heat shock 60kD protein 1 (chaperonin) , spastic paraplegia 13 (autosomal dominant) , SPG13; 60 kDa heat shock protein, mitochondrial; GROEL; HSP60; chaperonin 60; 60 kDa chaperonin; heat shock protein 65; P60 lymphocyte protein; mitochondrial matrix protein P1; short heat shock protein 60 Hsp60s1; HLD4; CPN60; HSP65; SPG13; HSP-60; HuCHA60
• Gene ID: 3329
• mRNA Refseq: NM_002156
• Protein Refseq: NP_002147
• MIM: 118190
• UniProt ID: P10809