Active Recombinant Human Histone Deacetylase 6, GST-tagged
Cat.No. : | HDAC6-397H |
Product Overview : | Full Length Human HDAC6–Class IIb, 160kD with GST tag. |
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Species : | Human |
Source : | Insect Cells |
Tag : | GST |
Description : | Histone deacetylase 6, also known as HDAC6, is a human gene. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. |
Purity : | Purified, active enzyme. |
Purification Procedure : | Glutathione Column |
Activity : | 1000 units per vial. 1 unit is defined as the amount of enzyme that will convert 1picomole per minute per ug of protein at pH8 at 30°C. |
Stability/Shelf-life : | >6 months from date of shipment |
Buffer Composition : | 25mM Tris pH8, 120mM NaCl, 0.05% Tween-20 & 40% Glycerol. |
Storage : | –80°C |
Full Length : | Full L. |
Gene Name | HDAC6 histone deacetylase 6 [ Homo sapiens ] |
Synonyms | HDAC6; FLJ16239; HD6; JM21; histone deacetylase 6; OTTHUMP00000032398; EC 3.5.1.98; KIAA0901. |
Gene ID | 10013 |
mRNA Refseq | NM_006044 |
Protein Refseq | NP_006035 |
MIM | 300272 |
UniProt ID | Q9UBN7 |
Chromosome Location | Xp11.23 |
Pathway | Gene Expression |
Function | actin binding; histone deacetylase activity; histone deacetylase binding; hydrolase activity; metal ion binding; specific transcriptional repressor activity; tubulin deacetylase activity; zinc ion binding |
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HDAC6-405H | Active Recombinant Human HDAC6, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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