Active Recombinant Human HERC4 Protein, GST-tagged

• Cat.No.: HERC4-637H
• Product Overview: Recombinant Human HERC4(642-end) fused with GST tag at N-terminal was expressed in Insect cells.

Specification

• Description: HERC4 or HECT and RLD domain containing E3 ubiquitin protein ligase 4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD domain is predicted to act as a guanine nucleotide exchange factor for small G proteins. HERC4 is highly expressed in adult and fetal brain and in all specific brain regions examined.
• Source: Insect cells
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol
• Bio-activity: 6 nmol/min/mg
• Molecular Mass: 71 kDa
• Protein length: 642-end
• Purity: >80%
• Applications: Ubiquitin Enzyme Assay, Western Blot
• Stability: 1 year at - 70 centigrade from the date of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 ug/ml

Gene Information

• Gene Name: HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 [ Homo sapiens ]
• Official Symbol: HERC4
• Synonyms: HERC4; HECT and RLD domain containing E3 ubiquitin protein ligase 4; hect domain and RLD 4; probable E3 ubiquitin-protein ligase HERC4; DKFZP564G092; KIAA1593; HECT domain and RCC1-like domain-containing protein 4; DKFZp564G092
• Gene ID: 26091
• mRNA Refseq: NM_015601
• Protein Refseq: NP_056416
• MIM: 609248
• UniProt ID: Q5GLZ8