Active Recombinant Human GFRA3 Protein, Fc Chimera

• Cat.No.: GFRA3-1005H
• Product Overview: Recombinant Human GFRA3 (Accession # O60609), fused with , was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Species: Human
• Source: CHO
• Tag: Fc
• Predicted N Terminal: Asp32
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.Immobilized Recombinant Human Artemin at 1 µg/mL can bind Recombinant Human GFR alpha -3/GDNF R alpha -3 Fc Chimera with an apparent KD < 2 nM.
• Molecular Mass: Recombinant Human GFRA3, Fc Chimera has a calculated MW of 64.8 kDa (monomer). In SDS-PAGE migrates as 75-90 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 10 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: GFRA3 GDNF family receptor alpha 3 [ Homo sapiens ]
• Official Symbol: GFRA3
• Synonyms: GFRA3; GDNF family receptor alpha 3; GDNF family receptor alpha-3; GFRa 3; GFR-alpha-3; GDNFR-alpha-3; GPI-linked receptor; GDNF receptor alpha-3; glial cell line-derived neurotrophic factor receptor alpha-3
• Gene ID: 2676
• mRNA Refseq: NM_001496
• Protein Refseq: NP_001487
• MIM: 605710
• UniProt ID: O60609
• Chromosome Location: 5q31.1-q31.3