Active Recombinant Human FLT3 Ligand Protein

• Cat.No.: FLT3LG-366H
• Product Overview: Recombinant Human FLT3 Ligand Protein is produced by Human Cells expression system. Structure: Glycosylated monomer.

Specification

• Species: Human
• Source: Human Cells
• Tag: Non
• Description: Human Flt3 Ligand is a 24-30kDa glycoprotein with a 158 amino acid.Flt3 Ligand is expressed by T cells, bone marrow and thymic fibroblasts. The predominant biologically active form is membrane- bound isoform, which can be proteolytically cleaved to generate a biologically active soluble isoform. Flt3 Ligand synergizes well with a number of other colony stimulating factors and interleukins to regulate proliferation of early hematopoietic cells by activating Flt3.
• Form: Lyophilized from a 0.2μm filtered solution in PBS without carrier protein
• Bio-activity: The activity was measured by its ability to stimulate the proliferation of the human acute myeloid leukemia cell line OCI-AML5.
• Molecular Mass: 24-30 kDa
• Endotoxin: <0.5EU/ug
• Purity: >95% by SDS-PAGE
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.
• Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Gene Information

• Gene Name: FLT3LG fms-related tyrosine kinase 3 ligand [ Homo sapiens ]
• Official Symbol: FLT3LG
• Synonyms: FLT3LG; flt3 ligand; FL; FLT3L
• Gene ID: 2323
• mRNA Refseq: NM_001204502
• Protein Refseq: NP_001191431
• MIM: 600007
• UniProt ID: P49771