Active Recombinant Human FGF3

• Cat.No.: FGF3-560H
• Product Overview: Recombinant Human FGF3 (Accession # NP_005238) Asp28-Arg212, fused with an N-terminal Met, was produced in E. coli.

Specification

• Species: Human
• Source: E.coli
• Protein Length: Asp28-Arg212
• Predicted N Terminal: Met
• Form: Lyophilized from a 0.2 µm filtered solution in MOPS, Na2SO4 and EDTA with BSA as a carrier protein.
• Bio-activity: Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al. (1988) Cancer Res. 48:4266; Thomas, K. et al. (1987) Methods Enzymol. 147:120.The ED50 for this effect is typically 0.02-0.1 µg/mL in the presence of 1 µg/mL of heparin.
• Molecular Mass: Recombinant Human FGF3, Met-tagged has a calculated MW of 21.1 kDa.
• Purity: >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: FGF3 fibroblast growth factor 3 [ Homo sapiens ]
• Official Symbol: FGF3
• Synonyms: FGF3; fibroblast growth factor 3; fibroblast growth factor 3 (murine mammary tumor virus integration site (v int 2) oncogene homolog) , INT2; HBGF 3; INT 2 proto oncogene protein; murine mammary tumor virus integration site 2; mouse; oncogene INT2; V INT2 murine mammary tumor virus integration site oncogene homolog; FGF-3; proto-oncogene Int-2; INT-2 proto-oncogene protein; heparin-binding growth factor 3; murine mammary tumor virus integration site 2, mouse; V-INT2 murine mammary tumor virus integration site oncogene homolog; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog); INT2; HBGF-3
• Gene ID: 2248
• mRNA Refseq: NM_005247
• Protein Refseq: NP_005238
• MIM: 164950
• UniProt ID: P11487
• Chromosome Location: 11q13