Active Recombinant Human FGF22 Protein

• Cat.No.: FGF22-035H
• Product Overview: The mature recombinant human FGF-22 protein consists of 148 amino acids (23-170) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Protein Length: 23-170 a.a.
• Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants.
• Bio-activity: Measured in a cell proliferation assay using 4MBr-5 rhesus monkey epithelial cells. The ED50 for this effect is 50-300 ng/mL.
• Molecular Mass: 18 kDa
• Product-Related Proteins: 23-170
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: FGF22 fibroblast growth factor 22 [ Homo sapiens (human) ]
• Official Symbol: FGF22
• Synonyms: FGF22; fibroblast growth factor 22; fibroblast growth factor 22; FGF-22
• Gene ID: 27006
• mRNA Refseq: NM_020637
• Protein Refseq: NP_065688
• MIM: 605831
• UniProt ID: Q9HCT0