Active Recombinant Human FGF20 Protein

• Cat.No.: FGF20-033H
• Product Overview: The mature recombinant human FGF-20 protein consists of 211 amino acids (1-211) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Protein Length: 1-211 a.a.
• Description: The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.
• Bio-activity: Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 0.2-1 ng/mL in the presence of 1 μg/mL of heparin.
• Molecular Mass: 24 kDa
• Product-Related Proteins: 1-211
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: FGF20 fibroblast growth factor 20 [ Homo sapiens (human) ]
• Official Symbol: FGF20
• Synonyms: FGF20; fibroblast growth factor 20; RHDA2; FGF-20; fibroblast growth factor 20
• Gene ID: 26281
• mRNA Refseq: NM_019851
• Protein Refseq: NP_062825
• MIM: 605558
• UniProt ID: Q9NP95