Active Recombinant Human EDAR, Fc-tagged, Biotinylated

• Cat.No.: EDAR-601H
• Product Overview: The recombinant human EDAR-Fc fusion is expressed as a 389 amino acid protein consisting of Glu27 - Ala187 region of EDAR (UniProt accession #Q9UNE0) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions

Specification

• Species: Human
• Source: Human Cells
• Tag: Fc
• Protein Length: 27-187 a.a.
• Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
• Bio-activity: Binds to its ligand EDA-A1 and blocks EDA-A1-mediated signaling activity.
• Molecular Mass: Calculated molecular mass (kDa): 42.9; Estimated by SDS-PAGE under reducing condition (kDa): 60-65
• Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the
• Purity: >95% judged by SDS-PAGE under reducing condition
• Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: EDAR ectodysplasin A receptor [ Homo sapiens ]
• Official Symbol: EDAR
• Synonyms: EDAR; ectodysplasin A receptor; DL, ectodysplasin 1, anhidrotic receptor , ED3; tumor necrosis factor receptor superfamily member EDAR; ED1R; ED5; EDA1R; EDA3; Edar; EDA-A1 receptor; downless homolog; ectodysplasin-A receptor; downless, mouse, homolog of; ectodermal dysplasia receptor; anhidrotic ectodysplasin receptor 1; ectodysplasin 1, anhidrotic receptor; DL; ED3; HRM1; EDA-A1R; FLJ94390
• Gene ID: 10913
• mRNA Refseq: NM_022336
• Protein Refseq: NP_071731
• MIM: 604095
• UniProt ID: Q9UNE0
• Chromosome Location: 2q13
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: protein binding; receptor activity; transmembrane signaling receptor activity