Active Recombinant Human DEFB4B

• Cat.No.: DEFB4B-009H
• Product Overview: Human DEFB4B (O15263, 24 a.a. - 64 a.a.) partial recombinant protein expressed in Escherichia coli.

Specification

• Species: Human
• Source: Human
• Tag: Non
• Protein Length: 24-64 a.a.
• Description: Beta-defensin 4B is a protein that in humans is encoded by the DEFB4B gene Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4B, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization.
• Sequence: VFGGIGDPVT CLKSGAICHP VFCPRRYKQI GTCGLPGTKC CKKP
• Theoretical MW (kDa): 4
• Form: Lyophilized
• Preparation Method: E. coli expression system
• Purity: > 98% by SDS-PAGE and HPLC
• Endotoxin Level: < 0.1 ng/ug (1 EU/ug)
• Activity: The ED50 was determined by its ability to chemoattract immature human dendritic cells using a concentration range of 1-50 ng/mL.
• Application: SDS-PAGE
• Storage Buffer: Lyophilized 100mM NaCl, 20mM PB, pH 7.4
• Storage: Store at -20°C on dry atmosphere for 2 years.After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.Aliquot to avoid repeated freezing and thawing.
• Unitprot ID: O15263

Gene Information

• Gene Name: DEFB4B defensin, beta 4B [ Homo sapiens ]
• Official Symbol: DEFB4B
• Synonyms: DEFB4P; DEFB4B; beta-defensin 4B; OTTHUMP00000223096; defensin, beta 4B, pseudogene
• Gene ID: 100289462
• mRNA Refseq: NM_001205266
• Protein Refseq: NP_001192195
• Chromosome Location: 8p23.1