Active Recombinant Human DDX1 Protein, Myc/DDK-tagged

• Cat.No.: DDX1-4893H
• Product Overview: Recombinant protein of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 (DDX1) with a Myc/DDK tag was expressed in HEK293T.

Specification

• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.
• Source: HEK293T
• Species: Human
• Tag: Myc&DDK
• Bio-activity: Biolayer interferometry (BLI) assay.
• Molecular Mass: 82.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: DDX1 DEAD-box helicase 1 [ Homo sapiens (human) ]
• Official Symbol: DDX1
• Synonyms: DDX1; DEAD-box helicase 1; DBP-RB; UKVH5d; ATP-dependent RNA helicase DDX1; DEAD (Asp-Glu-Ala-Asp) box helicase 1; DEAD (Asp-Glu-Ala-Asp) box polypeptide 1; DEAD box polypeptide 1; DEAD box protein 1; DEAD box protein retinoblastoma; DEAD box-1; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1; DEAD/H-box helicase 1; EC 3.6.4.13
• Gene ID: 1653
• mRNA Refseq: NM_004939
• Protein Refseq: NP_004930
• MIM: 601257
• UniProt ID: Q92499