Active Recombinant Human DAND5

• Cat.No.: DAND5-837H
• Product Overview: Recombinant Human DAND5 (Accession # NP_689867) Arg23-Ala189, fused with an N-terminal Met, was produced in E. coli.

Specification

• Species: Human
• Source: E.coli
• Protein Length: Arg23-Ala189
• Predicted N Terminal: Met
• Form: Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
• Bio-activity: Measured by its ability to inhibit BMP-4-induced activity in MC3T3-E1 mouse preosteoblast cells.The ED50 for this effect is typically 0.15 - 0.75 µg/mL in the presence of 50 ng/mL of rhBMP-4.
• Molecular Mass: Recombinant Human DAND5, Met-tagged has a calculated MW of 18.2 kDa (monomer).
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: DAND5 DAN domain family member 5, BMP antagonist [ Homo sapiens (human) ]
• Official Symbol: DAND5
• Synonyms: SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; CKTSF1B3; DAN domain family member 5; DAN domain family member 5; DAN domain family, member 5; cerberus 2; cerberus-like 2; cerberus-like protein 2; cerl-2; cysteine knot superfamily 1, BMP antagonist 3; gremlin-3
• Gene ID: 199699
• mRNA Refseq: NM_152654.2
• Protein Refseq: NP_689867.1
• MIM: 609068
• UniProt ID: Q8N907
• Chromosome Location: 19p13.